I think this is a great question..
In fact, it would likely be a COMBINATION
of the two to get the job done.
In a nutshell, I think manditory profiles provide the BASELINE
lockdown, then GPOs add "fine tuned" lockdown.
There's a bunch of stuff that you COULD do in a profile,
but are just too darned hard. Okay, why not just use GPOs?
So, the answer really is ... GPOs + MPs = Lockdown.


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