just my 2pence (cos I'm over the other side of the pond).....
1) Diskcleanup? Really? with Hard drives the same most modern machines have, disk cleanup is the last thing I'd be worrying about. Delete Temp files and dont worry.
2) If you really want to, why not just use the GPP's to schedule the cleanmgr.exe /sageset:n task?
3) Personally (and depending on the number of workstations you've got and the licensing in place) I'd go with pushing out a clean image with something like MDT. We go from blank drive to fully deployed machine in less than 45 mins. In some instances, it's easy to redeploy than patch!


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